Osteoarthritis guidelines: a progressive role for topical NSAIDs.
نویسنده
چکیده
Osteoarthritis (OA) is a potentially debilitating disorder that can place serious limitations on patient functionality and overall quality of life. Traditionally considered a disease of the elderly, more recent perceptions of OA reveal a broad spectrum of age and disease severity among patients. Because there are no curative or disease-modifying therapies for patients with OA at present, current approaches to management strive to relieve pain and increase functionality while minimizing the potential for adverse effects. Osteopathic physicians are particularly well positioned to achieve these goals, in light of their focus on manipulative treatment and their emphasis on total patient care.
منابع مشابه
Evolving guidelines in the use of topical nonsteroidal anti-inflammatory drugs in the treatment of osteoarthritis
BACKGROUND Nonsteroidal anti-inflammatory drugs (NSAIDs) are a standard treatment for osteoarthritis (OA), but the use of oral NSAIDs has been linked to an elevated risk for cardiovascular and gastrointestinal adverse events and renal toxicity. Topical NSAIDs are thought to afford efficacy that is comparable to oral formulations while reducing widespread systemic drug exposure, which may provid...
متن کاملClinical trial data in support of changing guidelines in osteoarthritis treatment
Goals for the management of osteoarthritis (OA) emphasize pain relief, reduction of inflammation, and improvement in functioning. Among pharmacological pain management interventions, nonsteroidal anti-inflammatory drugs (NSAIDs) are frequently recommended as the most effective treatment option for OA. However, the use of traditional oral NSAIDs is associated with risk of serious adverse events ...
متن کاملOsteoarthritis guidelines: a progressive role for topical nonsteroidal anti-inflammatory drugs
Current treatment guidelines for the treatment of chronic pain associated with osteoarthritis reflect the collective clinical knowledge of international experts in weighing the benefits of pharmacologic therapy options while striving to minimize the negative effects associated with them. Consideration of disease progression, pattern of flares, level of functional impairment or disability, respo...
متن کاملEfficacy of topical non-steroidal anti-inflammatory drugs in the treatment of osteoarthritis: meta-analysis of randomised controlled trials.
OBJECTIVE To assess the efficacy of topical non-steroidal anti-inflammatory drugs (NSAIDs) in the treatment of osteoarthritis. DATA SOURCES Medline, Embase, Scientific Citation Index, CINAHL, Cochrane Library, and abstracts from conferences. REVIEW METHODS Inclusion criterion was randomised controlled trials comparing topical NSAIDs with placebo or oral NSAIDs in osteoarthritis. Effect size...
متن کاملPrimary care Efficacy of topical non-steroidal anti-inflammatory drugs in the treatment of osteoarthritis: meta-analysis of randomised controlled trials
Objective To assess the efficacy of topical non-steroidal anti-inflammatory drugs (NSAIDs) in the treatment of osteoarthritis. Data sources Medline, Embase, Scientific Citation Index, CINAHL, Cochrane Library, and abstracts from conferences. Review methods Inclusion criterion was randomised controlled trials comparing topical NSAIDs with placebo or oral NSAIDs in osteoarthritis. Effect size was...
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ورودعنوان ژورنال:
- The Journal of the American Osteopathic Association
دوره 113 2 شماره
صفحات -
تاریخ انتشار 2013